Niki · AI Skin Advisor
Have a question about Dermaceutic Activabiome?
Dermaceutic Activabiome
Breakouts keep returning because most acne products treat the symptom, not the cause. Activabiome works overnight to rebalance your skin's microbiome — using 7% Glycolic Acid and 1% Salicylic Acid to clear pores, a marine algae-derived complex to inhibit bacteria and control sebum, and a 2% Microbiota Regulator to restore the biological conditions that keep skin clear long-term. Not for use during pregnancy.
SKU: SA-DERM-RES-ACT-001
SSL Secured Checkout. We never store your credit card details on this website.
Star Aesthetic
Star Light Rewards
Earn 60 Star Lights on this purchase
5% back in Star Lights on all treatments & products
1 Star Light = R1 of rewards value
Redeemable against any future visit or purchase
No sign-up needed — created on your first visit
Star Aesthetic
Gift Vouchers
The perfect gift for someone you love
Delivered by email · Valid 3 years · Redeemable on all treatments & products
Send a Gift Voucher →About This Product
Is Dermaceutic Activabiome right for you?
- Your acne or blemishes keep returning despite regular treatment
- You want to address the microbiome imbalance that drives persistent breakouts
- You have oily or combination skin prone to congestion and blackheads
- You want a comprehensive overnight treatment combining exfoliation, anti-bacterial, and microbiome support
- You are not pregnant or breastfeeding
How Dermaceutic Activabiome works — the science
The skin microbiome — the community of bacteria and microorganisms living on the skin surface — plays a fundamental role in acne formation. When balanced, beneficial bacteria keep Cutibacterium acnes under control. When disrupted by over-cleansing or harsh actives, C. acnes proliferates and blemishes recur.
Most anti-acne treatments kill bacteria but ignore the underlying microbiome balance — which is why blemishes return as soon as treatment stops. Activabiome addresses both levels. The 7% Glycolic Acid + 1% Salicylic Acid combination delivers comprehensive exfoliation: Glycolic Acid resurfaces the skin surface, while Salicylic Acid (being oil-soluble) penetrates into pores to dissolve sebum plugs and blackheads from within. The marine algae complex inhibits C. acnes activity and controls sebum. The 2% Microbiota Regulator restores the biological balance on the skin surface — creating conditions where beneficial bacteria thrive and C. acnes cannot dominate.
What you will notice — and when
Week 1–2: Skin feels cleaner and pores less congested. Initial mild purging possible. Week 3–4: Reduction in new blemish formation. Blackheads visibly reduced. Week 6–8: Significantly fewer breakouts. Skin clearer and more balanced. Month 3+: Long-term microbiome rebalancing — skin remains clear with consistent use.
How to use Dermaceutic Activabiome
- Apply in the evening after cleansing
- Apply a thin layer to the entire face, focusing on congested areas
- Allow to absorb — mild tingling from AHA/BHA combination is normal
- Follow with Hyal Ceutic moisturiser if needed
- Apply SPF50+ every morning — AHA use increases UV sensitivity
- Introduce gradually — begin 3 evenings per week and increase as skin adjusts
Key ingredients & what they do
| Ingredient | What it does for you |
|---|---|
| 7% Glycolic Acid | Resurfaces skin surface, removes dead cell buildup, and clears follicular debris |
| 1% Salicylic Acid (BHA) | Oil-soluble — penetrates into pores to dissolve sebum plugs and blackheads from within |
| Marine algae complex | Inhibits C. acnes bacteria and controls sebum production at the sebaceous gland |
| 2% Microbiota Regulator | Restores skin microbiome balance — creates conditions where beneficial bacteria prevent long-term C. acnes dominance |
Dr. Bangalee's clinical perspective
| Dr. Bangalee Recommends | Activabiome addresses the underlying microbiome disruption that causes recurring acne. I recommend it for patients who have persistent blemishes despite good skincare habits — the microbiome component means results are sustained rather than temporary. Combining Activabiome home care with Dermapen or chemical peel clinic visits gives patients both the structural correction and the biological balance they need for long-term clear skin. |
What our patients say
| I have had recurring acne since my 20s. Three months on Activabiome and I have had fewer breakouts than at any point in the past ten years. | My pores were cleaner and less congested within the first two weeks. By week six the improvement in my blemishes was dramatic. | Dr. Bangalee combined this with an in-clinic chemical peel. The combination cleared what years of different products could not. |
Frequently asked questions
| What is the skin microbiome and why does it matter for acne? | The skin microbiome is the community of microorganisms that live on your skin surface. A balanced microbiome keeps acne-causing bacteria in check. When disrupted, C. acnes dominates and blemishes become persistent. Restoring that balance is the key insight behind Activabiome. |
| Can I use Activabiome if I am on prescription acne treatment? | Consult Dr. Bangalee before combining with prescription actives — certain combinations require careful management to deliver the best results. |
| Is Activabiome suitable during pregnancy? | The AHA and BHA concentrations mean Activabiome is not recommended during pregnancy. Consult Dr. Bangalee for pregnancy-safe alternatives. |
Complete your routine
Step 1 — Cleanse PM Dermaceutic Advanced Cleanser | Step 2 — Treat PM Dermaceutic Activabiome | Step 3 — Moisturise PM Dermaceutic Hyal Ceutic | Step 4 — Protect AM Dermaceutic K Ceutic SPF 50 |
Complete Your Routine
Dermaceutic
Dermaceutic Activ Retinol 1.0
R 1 785,00
Dermaceutic
Dermaceutic Advanced Cleanser
R 760,00
Dermaceutic
Dermaceutic C25
R 1 240,00
Dermaceutic
Dermaceutic Dual Plus
R 1 870,00